3D-F10(32-179) [endoplasmic reticulum lumen]

Stable Identifier
R-HSA-159810
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
pro-factor X light chain, uncarboxylated
Icon
3D-F10(32-179) [endoplasmic reticulum lumen] icon
3D-F10(32-179) [endoplasmic reticulum lumen] icon
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
6871167 Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as beta-hydroxyaspartic acid

Kisiel, W, Fujikawa, K, Howald, WN, McMullen, BA, Sasagawa, T, Weinstein, B, Kwa, EY

Biochemistry 1983
836809 A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S

DiScipio, RG, Yates, SG, Hermodson, MA, Davie, EW

Biochemistry 1977
External Reference Information
External Reference
UniProt:P00742 F10
Gene Names
F10
Chain
signal peptide:1-31, propeptide:32-40, chain:41-488, chain:41-179, chain:183-488, propeptide:183-234, chain:235-488
Reference Genes
BioGPS Gene:2159 F10
COSMIC (genes):F10 F10
CTD Gene:2159 F10
dbSNP Gene:2159 F10
ENSEMBL:ENSG00000126218 F10
HGNC:3528 F10
KEGG:hsa:2159 F10
Monarch:2159 F10
NCBI Gene:2159 F10
OMIM:613872 F10
UCSC:P00742 F10
Reference Transcript
Other Identifiers
11723802_at
16776798
205620_PM_at
205620_at
2159
3502439
3502440
3502441
3502444
3502447
3502450
3502451
3502452
3502453
3502454
3502455
3502456
3502457
3502458
3502459
3502461
3502462
3502464
3502466
39979_at
7970241
A_23_P205177
A_33_P3319302
GE60493
GO:0002690
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005783
GO:0005788
GO:0005796
GO:0005886
GO:0006508
GO:0007596
GO:0008236
GO:0008289
GO:0009897
GO:0016787
GO:0030335
GO:0032008
GO:0043226
GO:0140096
HMNXSV003025274
HMNXSV003031147
ILMN_1670708
L29433_at
PH_hs_0024025
TC13000417.hg
g9961350_3p_at
g9961350_3p_x_at
Participates
as a component of
Other forms of this molecule
factor Xa heavy chain [plasma membrane]
11xCbxE-3D-F10(41-179) [plasma membrane]
factor Xa heavy chain [extracellular region]
11xCbxE-3D-F10(41-179) [extracellular region]
factor X heavy chain [extracellular region]
factor X activation peptide [extracellular region]
factor X heavy chain [endoplasmic reticulum lumen]
11xCbxE-3D-F10(32-179) [endoplasmic reticulum lumen]
factor X heavy chain [Golgi lumen]
11xCbxE-3D-F10(32-179) [Golgi lumen]
factor X light chain propeptide [Golgi lumen]
11xCbxE-3D-F10(41-179) [Golgi lumen]
Inferred To
F10 [endoplasmic reticulum lumen] (Canis familiaris)
F10 [endoplasmic reticulum lumen] (Gallus gallus)
F10 [endoplasmic reticulum lumen] (Mus musculus)
F10 [endoplasmic reticulum lumen] (Rattus norvegicus)
F10 [endoplasmic reticulum lumen] (Sus scrofa)
f10 [endoplasmic reticulum lumen] (Xenopus tropicalis)
proza [endoplasmic reticulum lumen] (Danio rerio)
F7 [endoplasmic reticulum lumen] (Bos taurus)
Modified Residues
Name
(2S,3R)-3-hydroxyaspartic acid at 103
Coordinate
103
PsiMod Name
(2S,3R)-3-hydroxyaspartic acid [MOD:00036]
PsiMod Definition
A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
3TK6, 2J38, 5JZ8, 2W3I, 7TPQ, 3ENS, 3KQC, 4BTI, 2BMG, 1IQI, 2J94, 7E6J, 2VVU, 2Y5H, 2RA0, 2VH0, 2VWM, 3Q3K, 2VH6, 6RK9, 2Y5G, 1LPK, 1G2L, 4Y71, 2D1J, 7BMI, 3CEN, 5K0H, 4Y6D, 7AHU, 2UWP, 2VWO, 5VOE, 2P93, 1IQG, 8EOK, 1XKA, 2Q1J, 1F0S, 1NFW, 2EI6, 3KQE, 2P3U, 1LQD, 2FZZ, 2J34, 6Q9I, 2UWL, 4Y7B, 3HPT, 6YYW, 3FFG, 6YYY, 2UWO, 2H9E, 2BQ7, 3KL6, 1MQ5, 2BQ6, 2Y80, 1IQK, 3LIW, 1G2M, 1IQE, 4A7I, 3M36, 7YBB, 4Y7A, 2XC0, 3SW2, 1IOE, 1F0R, 2P94, 1XKB, 5JZU, 7YB9, 2Y7Z, 2GD4, 4ZH8, 1NFU, 2PHB, 2EI7, 4BTU, 7TPP, 3CS7, 3TK5, 1C5M, 2J4I, 1LPG, 2VWL, 2P16, 2W3K, 2Y5F, 1MQ6, 1IQN, 6Q9F, 2W26, 1IQL, 2J95, 2P3F, 2XC4, 2VVC, 1NFY, 7YBC, 2XBW, 2WYG, 2BOK, 3M37, 4Y79, 2G00, 2P95, 2XBY, 2Y82, 7YB8, 2Y7X, 1LPZ, 1NFX, 2EI8, 1Z6E, 1V3X, 4BTT, 3KQB, 6Z6Q, 3K9X, 2J2U, 3KQD, 2XC5, 1EZQ, 2CJI, 2BQW, 2VVV, 6YYX, 1FXY, 2XBV, 5JQY, 1WU1, 3IIT, 1IQM, 5JTC, 1IQJ, 5VOF, 2P3T, 2PR3, 7BMJ, 1FAX, 4Y76, 2VWN, 6Z6R, 2BOH, 1FJS, 2XBX, 1IQH, 1KSN, 2WYJ, 1IQF, 2JKH, 1HCG, 2Y81, 4ZHA, 1P0S
ZINC - Investigational
HPA
Pharos - Targets
Orphanet
F10
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (3)
Cite Us!