factor Xa heavy chain [extracellular region]

Stable Identifier
R-HSA-140688
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
F10(235-488)
Icon
factor Xa heavy chain [extracellular region] icon
factor Xa heavy chain [extracellular region] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
921929 Activation of human factor X (Stuart factor) by a protease from Russell's viper venom

DiScipio, RG, Hermodson, MA, Davie, EW

Biochemistry 1977
6587384 Characterization of a cDNA coding for human factor X

Kisiel, W, Chung, DW, Leytus, SP, Kurachi, K, Davie, EW

Proc Natl Acad Sci U S A 1984
External Reference Information
External Reference
UniProt:P00742 F10
Gene Names
F10
Chain
signal peptide:1-31, propeptide:32-40, chain:41-488, chain:41-179, chain:183-488, propeptide:183-234, chain:235-488
Reference Genes
BioGPS Gene:2159 F10
COSMIC (genes):F10 F10
CTD Gene:2159 F10
dbSNP Gene:2159 F10
ENSEMBL:ENSG00000126218 F10
ENSEMBL_homo_sapiens_GENE:ENSG00000126218.12 F10
HGNC:3528 F10
KEGG Gene (Homo sapiens):2159 F10
Monarch:2159 F10
NCBI Gene:2159 F10
OMIM:613872 F10
Reference Transcript
Other Identifiers
11723802_at
16776798
205620_PM_at
205620_at
2159
3502440
3502441
3502444
3502447
3502450
3502452
3502453
3502455
3502456
3502457
3502458
3502459
39979_at
7970241
A_23_P205177
GE60493
GO:0003824
GO:0004252
GO:0005509
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0006508
GO:0007596
GO:0007599
GO:0008233
GO:0008236
GO:0008289
GO:0009897
GO:0016787
GO:0023052
GO:0030335
GO:0032008
GO:0042060
GO:0043226
GO:0048870
GO:0140096
HMNXSV003031147
ILMN_1670708
L29433_at
PH_hs_0024025
TC13000417.hg
g9961350_3p_at
g9961350_3p_x_at
Participates
as a component of
Other forms of this molecule
11xCbxE-3D-F10(41-179) [Golgi lumen]
factor X light chain propeptide [Golgi lumen]
11xCbxE-3D-F10(32-179) [Golgi lumen]
factor X heavy chain [Golgi lumen]
11xCbxE-3D-F10(32-179) [endoplasmic reticulum lumen]
factor X heavy chain [endoplasmic reticulum lumen]
3D-F10(32-179) [endoplasmic reticulum lumen]
factor X activation peptide [extracellular region]
factor X heavy chain [extracellular region]
11xCbxE-3D-F10(41-179) [extracellular region]
11xCbxE-3D-F10(41-179) [plasma membrane]
factor Xa heavy chain [plasma membrane]
Inferred To
f10 [extracellular region] (Xenopus tropicalis)
F7 [extracellular region] (Bos taurus)
F10 [extracellular region] (Canis familiaris)
F10 [extracellular region] (Gallus gallus)
F10 [extracellular region] (Mus musculus)
F10 [extracellular region] (Rattus norvegicus)
F10 [extracellular region] (Sus scrofa)
proza [extracellular region] (Danio rerio)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
3ENS, 2VWO, 3KQC, 6Q9I, 5VOF, 6YYW, 2UWL, 1IQI, 4ZH8, 2P3F, 2WYJ, 2J2U, 2J4I, 3FFG, 2Y7X, 2UWP, 1IQK, 5JQY, 1LPK, 2XBW, 1G2M, 5JZ8, 1NFU, 1IQE, 1XKB, 2EI7, 1FAX, 2J94, 3KQE, 2Y5H, 1V3X, 2PR3, 2XBY, 2BMG, 4Y71, 4BTT, 6Z6R, 3SW2, 1IQG, 2XC5, 1FJS, 7YB9, 5JZU, 1C5M, 2PHB, 1MQ6, 2P94, 2VVV, 7TPP, 2Y81, 7BMI, 2J34, 1P0S, 4Y7B, 4A7I, 3TK6, 1IQM, 2EI8, 4Y76, 2BQW, 5K0H, 5JTC, 2VVC, 3Q3K, 2VWM, 1IQN, 2BOH, 6Z6Q, 2W3K, 6YYY, 1NFX, 2P3T, 1FXY, 7YBB, 2VH6, 2BQ6, 1F0R, 2UWO, 1IQH, 6YYX, 4BTI, 3KQD, 3CS7, 4Y6D, 2VWN, 2D1J, 6Q9F, 1XKA, 1IQJ, 2WYG, 5VOE, 2Y7Z, 3KQB, 1F0S, 1LPG, 2VVU, 3IIT, 2Q1J, 2XBV, 2G00, 2FZZ, 1G2L, 2Y82, 2J38, 1Z6E, 3CEN, 1NFW, 3M36, 2EI6, 2H9E, 2GD4, 2Y5G, 2XC0, 2XBX, 2W26, 1HCG, 1LPZ, 3K9X, 2J95, 4BTU, 4ZHA, 1IQF, 1KSN, 2P16, 1MQ5, 2CJI, 2BOK, 7YB8, 8EOK, 2BQ7, 2XC4, 1LQD, 3KL6, 7BMJ, 3M37, 3HPT, 1EZQ, 2P93, 2Y80, 4Y7A, 3TK5, 7TPQ, 1IQL, 2VH0, 6RK9, 4Y79, 7E6J, 1IOE, 2P95, 3LIW, 7AHU, 1WU1, 2JKH, 2RA0, 2W3I, 1NFY, 7YBC, 2VWL, 2P3U, 2Y5F
ZINC - Investigational
HPA
GeneCards
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (3)
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