Reactome | F10 [endoplasmic reticulum lumen]

F10 [endoplasmic reticulum lumen]

Stable Identifier

R-CFA-159810

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum lumen

Synonyms

3D-F10(32-179), A0A8I3PQV5

Locations in the PathwayBrowser

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Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
    - Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Canis familiaris)
      - Gamma-carboxylation of protein precursors (Canis familiaris)
        
        GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Canis familiaris)
        
        pro-factor X, uncarboxylated [endoplasmic reticulum lumen] (Canis familiaris)
        
        F10 [endoplasmic reticulum lumen] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PQV5

Gene Names

F10

Reference Genes

BioGPS Gene:476993 F10

ENSEMBL:ENSCAFG00845024167.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845024167.1 F10

Monarch:476993 F10

NCBI Gene:476993 F10

Reference Transcript

RefSeq:XM_534191.6 F10

Other Identifiers

476993

Cfa.12187.1.A1_at

CfaAffx.10361.1.S1_s_at

GO:0003824

GO:0004252

GO:0005509

GO:0005543

GO:0005576

GO:0006508

GO:0007596

GO:0007599

GO:0008289

GO:0016787

GO:0023052

GO:0032008

GO:0042060

GO:0140096

Participates

as a component of

pro-factor X, uncarboxylated [endoplasmic reticulum lumen] (Canis familiaris)

Other forms of this molecule

F10 [Golgi lumen]

F10 [endoplasmic reticulum lumen]

F10 [extracellular region]

F10 [plasma membrane]

Inferred From

3D-F10(32-179) [endoplasmic reticulum lumen] (Homo sapiens)

Modified Residues

Name

(2S,3R)-3-hydroxyaspartic acid at 103 (in Homo sapiens)

Coordinate

103

PsiMod Name

(2S,3R)-3-hydroxyaspartic acid [MOD:00036]

PsiMod Definition

A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid.

Cross References

RefSeq

XP_534191.1

OpenTargets

ENSG00000126218

Ensembl

ENSCAFG00845024167, ENSCAFT00845042678, ENSCAFP00845033467

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