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Transport of Mature mRNA derived from an Intron-Containing Transcript
Stable Identifier
R-HSA-159236
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
,
nuclear envelope
,
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
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Transport of mRNA from the nucleus to the cytoplasm, where it is translated into protein, is highly selective and closely coupled to correct RNA processing. This coupling is achieved by the nuclear pore complex, which recognizes and transports only completed mRNAs.
Participants
Events
NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)
(Homo sapiens)
Docking of the TAP:EJC Complex with the NPC
(Homo sapiens)
Transport of the export-competent mRNP complex through the NPC
(Homo sapiens)
mRNP complex dissociates from cytosolic face of NPC
(Homo sapiens)
Participates
as an event of
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Event Information
Go Biological Process
mRNA export from nucleus (0006406)
Orthologous Events
Transport of Mature mRNA derived from an Intron-Containing Transcript (Bos taurus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Caenorhabditis elegans)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Canis familiaris)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Drosophila melanogaster)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Gallus gallus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Mus musculus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Rattus norvegicus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Saccharomyces cerevisiae)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Schizosaccharomyces pombe)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Sus scrofa)
Created
Gillespie, ME (2005-02-27)
© 2024
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