Reactome | mRNP complex dissociates from cytosolic face of NPC

mRNP complex dissociates from cytosolic face of NPC

Stable Identifier

R-HSA-75098

Type

Reaction

Species

Homo sapiens

Compartment

cytosol, nuclear envelope

Synonyms

Release from the NPC and Disassembly of the mRNP

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

mRNP complex dissociates from cytosolic face of NPC

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of and 1 molecule of 'Export Receptor bound mature mRNA Complex' are present. At the end of this reaction, 1 molecule of 'THOC4(Aly/Ref)', 1 molecule of 'Mature mRNP Complex', 1 molecule of 'SRm160', and 1 molecule of 'TAP' are present.

This reaction takes place in the 'cytoplasm'.

Literature References

PubMed ID	Title	Journal	Year
18423201	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs Jülich, K, Ma, XM, Blenis, J, Richardson, CJ, Yoon, SO	Cell	2008
12093754	The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling Maquat, LE, Lejeune, F, Ishigaki, Y, Li, X	EMBO J.	2002