CL is hydrolyzed to MLCL by PLA2G6 (IM)

Stable Identifier
R-HSA-1482778
Type
Reaction
Species
Homo sapiens
Compartment
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At the inner mitochondrial membrane (IM), calcium-independent phospholipase A2 gamma (PLA2G6) hydrolyzes, removing one of the acyl chains, cardiolipin (CL) to form monolysocardiolipin (MLCL). This reaction is inferred from rats. PLA2G6 has also been characterized in humans (Larsson et al. 1998, Ma et al. 1999, Larsson Forsell et al. 1999).

Participants
Participates
Catalyst Activity

phospholipase A2 activity of PLA2G6 [mitochondrial inner membrane]

Inferred From
Authored
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