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PLA2G6 [mitochondrial inner membrane]
Stable Identifier
R-HSA-1524076
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
iPLA2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodeling of CL (Homo sapiens)
CL is hydrolyzed to MLCL by PLA2G6 (IM) (Homo sapiens)
PLA2G6 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60733 PLA2G6
Gene Names
PLA2G6, PLPLA9
Chain
chain:1-806
Reference Genes
BioGPS Gene:8398 PLA2G6
COSMIC (genes):PLA2G6 PLA2G6
CTD Gene:8398 PLA2G6
dbSNP Gene:8398 PLA2G6
ENSEMBL:ENSG00000184381 PLA2G6
HGNC:9039 PLA2G6
KEGG:hsa:8398 PLA2G6
Monarch:8398 PLA2G6
NCBI Gene:8398 PLA2G6
OMIM:603604 PLA2G6
UCSC:O60733 PLA2G6
Reference Transcript
RefSeq:XM_005261765.1 PLA2G6
RefSeq:XM_006724332.3 PLA2G6
RefSeq:XM_005261766.1 PLA2G6
RefSeq:XM_017028988.1 PLA2G6
RefSeq:NM_001004426.1 PLA2G6
RefSeq:XM_005261764.2 PLA2G6
RefSeq:XM_017028981.1 PLA2G6
RefSeq:NM_003560.2 PLA2G6
RefSeq:NM_001199562.1 PLA2G6
RefSeq:XM_017028982.1 PLA2G6
Other Identifiers
11739203_a_at
11747636_a_at
11754682_a_at
11760980_at
16934929
204691_PM_x_at
204691_x_at
210647_PM_x_at
210647_x_at
215938_3p_s_at
215938_PM_s_at
215938_s_at
3960385
3960387
3960389
3960390
3960391
3960392
3960393
3960394
3960395
3960398
3960399
3960400
3960401
3960402
3960403
3960404
3960405
3960406
3960407
3960408
3960409
3960410
3960411
3960412
3960413
3960414
3960415
3960416
3960417
3960418
3960419
3960420
3960421
3960422
3960423
3960424
3960425
3960426
3960427
3960429
3960430
3960433
3960436
3960437
41645_at
8076025
8398
85242_at
A_23_P6464
A_33_P3421821
GE54590
GE597043
GO:0002376
GO:0003824
GO:0003847
GO:0004622
GO:0004623
GO:0005515
GO:0005516
GO:0005615
GO:0005737
GO:0005739
GO:0005829
GO:0005856
GO:0005886
GO:0006629
GO:0006935
GO:0015630
GO:0016020
GO:0016042
GO:0016607
GO:0016787
GO:0017171
GO:0019731
GO:0031143
GO:0032049
GO:0034638
GO:0035774
GO:0035965
GO:0038096
GO:0042802
GO:0042995
GO:0043226
GO:0046338
GO:0046469
GO:0046473
GO:0047499
GO:0052816
GO:0098542
GO:2000304
HMNXSV003009651
HMNXSV003035126
Hs.120360.2.S1_3p_a_at
ILMN_1697654
ILMN_1798955
PH_hs_0023690
PH_hs_0032618
g5305593_3p_s_at
Other forms of this molecule
PLA2G6 [cytosol]
Cross References
RefSeq
XP_016884477.1
,
NP_001004426.1
,
XP_006724395.1
,
NP_001186491.1
,
XP_005261821.1
,
NP_003551.2
,
XP_005261823.1
,
XP_016884471.1
,
XP_016884470.1
,
XP_005261822.1
Guide to Pharmacology - Targets
1431
OpenTargets
ENSG00000184381
ENSEMBL
ENSP00000335149
,
ENST00000335539
,
ENSP00000499555
,
ENSP00000499712
,
ENSP00000499665
,
ENST00000402064
,
ENST00000663895
,
ENST00000667521
,
ENSG00000184381
,
ENSP00000386100
,
ENSP00000333142
,
ENST00000332509
,
ENST00000660610
ZINC - Substances
PLPL9_HUMAN
ZINC target
O60733
PRO
O60733
IntEnz
3.1.2.2
HPA
ENSG00000184381-PLA2G6
GeneCards
PLA2G6
Pharos - Targets
O60733
Orphanet
PLA2G6
ZINC - Predictions - Purchasable
PLPL9_HUMAN
HMDB Protein
HMDBP00068
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NZL9 MAT2B
3
MAT2B [mitochondrial outer membrane]
(R-HSA-5696871)
PolyUb-MAT2B [mitochondrial outer membrane]
(R-HSA-6783129)
MAT2B [cytosol]
(R-HSA-351214)
0.556
3
UniProt:O95199 RCBT2
0.556
3
UniProt:O60733 PLA2G6
2
PLA2G6 [cytosol]
(R-HSA-201596)
PLA2G6 [mitochondrial inner membrane]
(R-HSA-1524076)
0.556
3
UniProt:Q14140 SRTD2
0.556
3
UniProt:Q8N1F7 NUP93
2
NUP93 [nuclear envelope]
(R-HSA-157749)
NUP93 [cytosol]
(R-HSA-9634167)
0.556
3
UniProt:B2RXF5 ZBT42
0.556
3
UniProt:Q70EL1-9 USP54
0.556
3
UniProt:Q86XT4 TRIM50
1
TRIM50 [cytosol]
(R-HSA-5688976)
0.556
3
IntAct:EBI-16439879 CCSB ORF ID
0.556
3
UniProt:Q9BVN2 RUSC1
0.556
3
UniProt:Q8TAP6 CEP76
1
CEP76 [cytosol]
(R-HSA-380281)
0.556
3
UniProt:Q9NWT6 HIF1AN
1
HIF1AN [cytosol]
(R-HSA-1234154)
0.527
2
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