p-5S,T642-AS160:IRAP [cytoplasmic vesicle membrane]

Stable Identifier
R-HSA-1445133
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
Phosphorylated TBC1D4:LNPEP
Locations in the PathwayBrowser
General

AS160 (TBC1D4) phosphorylated on serines 318, 341, 570, 588, and 751 and threonine 642 binds to all 14-3-3 proteins, although binding to 14-3-3 delta (YWHAZ) is comparatively low (Ramm et al. 2006, Howlett et al. 2007, Ngo et al. 2009, Treebak et al. 2009, Koumanov et al. 2011). As inferred from mouse, binding to 14-3-3 does not interfere with the interaction between AS160 and IRAP (LNPEP).

Participants
Participant Of
Inferred From