inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate

Stable Identifier
R-GGA-421174
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate
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Cytosolic NP (purine nucleoside phosphorylase) catalyzes the reversible reaction of inosine and orthophosphate to form hypoxanthine and D-ribose 1-phosphate. Chicken NP is known only as the predicted protein product of a gene found by computational analysis of the genomic DNA sequence; the reaction shown here is inferred from its better-studied human counterpart.
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Output
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Catalyst Activity

purine-nucleoside phosphorylase activity of NP [cytosol]

Physical Entity
NP [cytosol] (Gallus gallus)
Activity
purine-nucleoside phosphorylase activity (GO:0004731)
Inferred From
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-15)
Created
D'Eustachio, P  (2009-05-15)
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