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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
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Content Service
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
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Computationally inferred events
FAQ
Linking to Us
Citing us
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Analyse gene list
Analyse gene expression
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Go!
Ino [cytosol]
Stable Identifier
R-ALL-83927
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
inosine
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Abacavir ADME (Bos taurus)
Abacavir metabolism (Bos taurus)
carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)
Ino [cytosol]
Ribavirin ADME (Bos taurus)
NT5C2 tetramer phosphorylates RBV (Bos taurus)
Ino [cytosol]
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Bos taurus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Bos taurus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Bos taurus)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
ADA catalyzes the deamination of (deoxy)adenosine (Bos taurus)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Bos taurus)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Bos taurus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Bos taurus)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Bos taurus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Bos taurus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Bos taurus)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Bos taurus)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Caenorhabditis elegans)
Abacavir ADME (Caenorhabditis elegans)
Abacavir metabolism (Caenorhabditis elegans)
carbovir + IMP => carbovir monophosphate + inosine (Caenorhabditis elegans)
Ino [cytosol]
Ribavirin ADME (Caenorhabditis elegans)
NT5C2 tetramer phosphorylates RBV (Caenorhabditis elegans)
Ino [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Caenorhabditis elegans)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Caenorhabditis elegans)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
ADA catalyzes the deamination of (deoxy)adenosine (Caenorhabditis elegans)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Caenorhabditis elegans)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Caenorhabditis elegans)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Caenorhabditis elegans)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Caenorhabditis elegans)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Caenorhabditis elegans)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Caenorhabditis elegans)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Caenorhabditis elegans)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Canis familiaris)
Abacavir ADME (Canis familiaris)
Abacavir metabolism (Canis familiaris)
carbovir + IMP => carbovir monophosphate + inosine (Canis familiaris)
Ino [cytosol]
Ribavirin ADME (Canis familiaris)
NT5C2 tetramer phosphorylates RBV (Canis familiaris)
Ino [cytosol]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Canis familiaris)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Canis familiaris)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Canis familiaris)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
ADA catalyzes the deamination of (deoxy)adenosine (Canis familiaris)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Canis familiaris)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Canis familiaris)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Canis familiaris)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Canis familiaris)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Canis familiaris)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Canis familiaris)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Danio rerio)
Abacavir ADME (Danio rerio)
Abacavir metabolism (Danio rerio)
carbovir + IMP => carbovir monophosphate + inosine (Danio rerio)
Ino [cytosol]
Ribavirin ADME (Danio rerio)
NT5C2 tetramer phosphorylates RBV (Danio rerio)
Ino [cytosol]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Danio rerio)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Danio rerio)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Danio rerio)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
ADA catalyzes the deamination of (deoxy)adenosine (Danio rerio)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Danio rerio)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Danio rerio)
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Danio rerio)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Danio rerio)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Danio rerio)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Danio rerio)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Danio rerio)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Danio rerio)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Danio rerio)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Dictyostelium discoideum)
Abacavir ADME (Dictyostelium discoideum)
Abacavir metabolism (Dictyostelium discoideum)
carbovir + IMP => carbovir monophosphate + inosine (Dictyostelium discoideum)
Ino [cytosol]
Ribavirin ADME (Dictyostelium discoideum)
NT5C2 tetramer phosphorylates RBV (Dictyostelium discoideum)
Ino [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Dictyostelium discoideum)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Dictyostelium discoideum)
Purine salvage (Dictyostelium discoideum)
ADA catalyzes the deamination of (deoxy)adenosine (Dictyostelium discoideum)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Dictyostelium discoideum)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Dictyostelium discoideum)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Dictyostelium discoideum)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Dictyostelium discoideum)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Drosophila melanogaster)
Abacavir ADME (Drosophila melanogaster)
Abacavir metabolism (Drosophila melanogaster)
carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)
Ino [cytosol]
Ribavirin ADME (Drosophila melanogaster)
NT5C2 tetramer phosphorylates RBV (Drosophila melanogaster)
Ino [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Drosophila melanogaster)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Drosophila melanogaster)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Drosophila melanogaster)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Drosophila melanogaster)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Drosophila melanogaster)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Drosophila melanogaster)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Drosophila melanogaster)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Drosophila melanogaster)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Drosophila melanogaster)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Gallus gallus)
Abacavir ADME (Gallus gallus)
Abacavir metabolism (Gallus gallus)
carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)
Ino [cytosol]
Ribavirin ADME (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Gallus gallus)
Ino [cytosol]
Metabolism (Gallus gallus)
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
Urate synthesis (Gallus gallus)
inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate (Gallus gallus)
Ino [cytosol]
inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)
Ino [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Gallus gallus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Gallus gallus)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Gallus gallus)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Gallus gallus)
nucleosides [cytosol]
Ino [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of nucleotide metabolism (Homo sapiens)
Nucleotide catabolism defects (Homo sapiens)
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine (Homo sapiens)
Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)
Ino, dI [cytosol]
Ino [cytosol]
Drug ADME (Homo sapiens)
Abacavir ADME (Homo sapiens)
Abacavir metabolism (Homo sapiens)
carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)
Ino [cytosol]
Ribavirin ADME (Homo sapiens)
NT5C2 tetramer phosphorylates RBV (Homo sapiens)
Ino [cytosol]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Homo sapiens)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Homo sapiens)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Homo sapiens)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
ADA catalyzes the deamination of (deoxy)adenosine (Homo sapiens)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Homo sapiens)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Homo sapiens)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Homo sapiens)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Homo sapiens)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Homo sapiens)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Mus musculus)
Abacavir ADME (Mus musculus)
Abacavir metabolism (Mus musculus)
carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)
Ino [cytosol]
Ribavirin ADME (Mus musculus)
NT5C2 tetramer phosphorylates RBV (Mus musculus)
Ino [cytosol]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Mus musculus)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Mus musculus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Mus musculus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Mus musculus)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
ADA catalyzes the deamination of (deoxy)adenosine (Mus musculus)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Mus musculus)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Mus musculus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Mus musculus)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Mus musculus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Mus musculus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Mus musculus)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Mus musculus)
nucleosides [cytosol]
Ino [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide salvage (Plasmodium falciparum)
Purine salvage (Plasmodium falciparum)
ADA catalyzes the deamination of (deoxy)adenosine (Plasmodium falciparum)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Plasmodium falciparum)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Plasmodium falciparum)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Plasmodium falciparum)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Plasmodium falciparum)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Rattus norvegicus)
Abacavir ADME (Rattus norvegicus)
Abacavir metabolism (Rattus norvegicus)
carbovir + IMP => carbovir monophosphate + inosine (Rattus norvegicus)
Ino [cytosol]
Ribavirin ADME (Rattus norvegicus)
NT5C2 tetramer phosphorylates RBV (Rattus norvegicus)
Ino [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Rattus norvegicus)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Rattus norvegicus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Rattus norvegicus)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Rattus norvegicus)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
ADA catalyzes the deamination of (deoxy)adenosine (Rattus norvegicus)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Rattus norvegicus)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Rattus norvegicus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Rattus norvegicus)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Rattus norvegicus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Rattus norvegicus)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Rattus norvegicus)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Rattus norvegicus)
nucleosides [cytosol]
Ino [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide catabolism (Saccharomyces cerevisiae)
Purine catabolism (Saccharomyces cerevisiae)
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Saccharomyces cerevisiae)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Saccharomyces cerevisiae)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of vitamins, nucleosides, and related molecules (Saccharomyces cerevisiae)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Saccharomyces cerevisiae)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Saccharomyces cerevisiae)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Saccharomyces cerevisiae)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Saccharomyces cerevisiae)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Saccharomyces cerevisiae)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Saccharomyces cerevisiae)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Saccharomyces cerevisiae)
nucleosides [cytosol]
Ino [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide catabolism (Schizosaccharomyces pombe)
Purine catabolism (Schizosaccharomyces pombe)
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Schizosaccharomyces pombe)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Schizosaccharomyces pombe)
Ino, dI [cytosol]
Ino [cytosol]
Drug ADME (Sus scrofa)
Abacavir ADME (Sus scrofa)
Abacavir metabolism (Sus scrofa)
carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)
Ino [cytosol]
Ribavirin ADME (Sus scrofa)
NT5C2 tetramer phosphorylates RBV (Sus scrofa)
Ino [cytosol]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Sus scrofa)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Sus scrofa)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Sus scrofa)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Sus scrofa)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
ADA catalyzes the deamination of (deoxy)adenosine (Sus scrofa)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Sus scrofa)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Sus scrofa)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Sus scrofa)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Sus scrofa)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Sus scrofa)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Sus scrofa)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Sus scrofa)
nucleosides [cytosol]
Ino [cytosol]
Drug ADME (Xenopus tropicalis)
Abacavir ADME (Xenopus tropicalis)
Abacavir metabolism (Xenopus tropicalis)
carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)
Ino [cytosol]
Ribavirin ADME (Xenopus tropicalis)
NT5C2 tetramer phosphorylates RBV (Xenopus tropicalis)
Ino [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Xenopus tropicalis)
(d)A, (d)G, (d)I [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Xenopus tropicalis)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Xenopus tropicalis)
Gu-Rib, dG, Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Xenopus tropicalis)
Ino, dI [cytosol]
Ino [cytosol]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
ADA catalyzes the deamination of (deoxy)adenosine (Xenopus tropicalis)
Ino, dI [cytosol]
Ino [cytosol]
PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Xenopus tropicalis)
Ino, dI [cytosol]
Ino [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Xenopus tropicalis)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Xenopus tropicalis)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Xenopus tropicalis)
ligands of SLC28A2 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Xenopus tropicalis)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Xenopus tropicalis)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Xenopus tropicalis)
ligands of SLC28A3 & 29A1 [cytosol]
Ino [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Xenopus tropicalis)
ligands of SLC29A2 [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Xenopus tropicalis)
nucleosides [cytosol]
Ino [cytosol]
SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Xenopus tropicalis)
nucleosides [cytosol]
Ino [cytosol]
External Reference Information
External Reference
inosine [ChEBI:17596]
Participates
as an output of
inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Dictyostelium discoideum)
NT5C2 tetramer phosphorylates RBV (Caenorhabditis elegans)
NT5C2 tetramer phosphorylates RBV (Drosophila melanogaster)
NT5C2 tetramer phosphorylates RBV (Gallus gallus)
NT5C2 tetramer phosphorylates RBV (Xenopus tropicalis)
NT5C2 tetramer phosphorylates RBV (Danio rerio)
NT5C2 tetramer phosphorylates RBV (Sus scrofa)
NT5C2 tetramer phosphorylates RBV (Bos taurus)
NT5C2 tetramer phosphorylates RBV (Canis familiaris)
NT5C2 tetramer phosphorylates RBV (Rattus norvegicus)
NT5C2 tetramer phosphorylates RBV (Mus musculus)
NT5C2 tetramer phosphorylates RBV (Homo sapiens)
carbovir + IMP => carbovir monophosphate + inosine (Dictyostelium discoideum)
carbovir + IMP => carbovir monophosphate + inosine (Caenorhabditis elegans)
carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)
carbovir + IMP => carbovir monophosphate + inosine (Gallus gallus)
carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)
carbovir + IMP => carbovir monophosphate + inosine (Danio rerio)
carbovir + IMP => carbovir monophosphate + inosine (Sus scrofa)
carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)
carbovir + IMP => carbovir monophosphate + inosine (Canis familiaris)
carbovir + IMP => carbovir monophosphate + inosine (Rattus norvegicus)
carbovir + IMP => carbovir monophosphate + inosine (Mus musculus)
carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)
as an input of
inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate (Gallus gallus)
as a member of
ligands of SLC29A2 [cytosol]
nucleosides [cytosol]
ligands of SLC28A2 [cytosol]
ligands of SLC28A3 & 29A1 [cytosol]
(d)A, (d)G, (d)I [cytosol]
Gu-Rib, dG, Ino, dI [cytosol]
Ino, dI [cytosol]
Other forms of this molecule
Ino [lysosomal lumen]
Ino [extracellular region]
Cross References
Guide to Pharmacology - Ligands
4554
COMPOUND
C00294
PubChem Substance
8144594
HMDB Metabolite
HMDB0000195
ZINC
000008855117
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