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Urate synthesis
Stable Identifier
R-GGA-421178
Type
Pathway
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Gallus gallus)
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
Urate synthesis (Gallus gallus)
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The conversion of inosine monophosphate (IMP) to urate is the major route by which excess nitrogen is excreted from the body in chickens and other birds (Krebs 1977).
Literature References
PubMed ID
Title
Journal
Year
358796
Regulatory mechanisms in purine biosynthesis
Krebs, HA
Adv Enzyme Regul
1977
Participants
Events
inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate
(Gallus gallus)
inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate
(Gallus gallus)
hypoxanthine + H2O + NAD+ => xanthine + NADH + H+
(Gallus gallus)
xanthine + H2O + NAD+ => urate + NADH + H+
(Gallus gallus)
Participates
as an event of
Purine metabolism (Gallus gallus)
Event Information
Go Biological Process
urate biosynthetic process (0034418)
Authored
D'Eustachio, P (2009-05-15)
Reviewed
D'Eustachio, P (2009-05-15)
Created
D'Eustachio, P (2009-05-15)
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