2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+

Stable Identifier
R-FCA-164926
Type
Reaction [transition]
Species
Felis catus
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+
This reaction has been characterized in vitro using enzyme partially purified from cat liver (Ichiyama et al. 1965). The human event is inferred from the cat one. Neither the cat nor the human protein has been fully purified or sequenced.
Literature References
PubMed ID Title Journal Year
14275130 Studies on the metabolism of the benzene ring of tryptophan in mammalian tissues. II. Enzymatic formation of alpha-muconic acid from 2-hydroxyanthranilic acid

Ichiyama, A, Nakamura, S, Kawai, H, Honjo, T, Nishizuka, Y, Hayaishi, O, Senoh, S

J Biol Chem 1965
Participants
Input
Output
Catalyst Activity

aminomuconate-semialdehyde dehydrogenase activity of aminomuconate-semialdehyde dehydrogenase [cytosol]

Physical Entity
aminomuconate-semialdehyde dehydrogenase [cytosol] (Felis catus)
Activity
aminomuconate-semialdehyde dehydrogenase activity (GO:0047102)
Orthologous Events
2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ (Homo sapiens)
Authored
D'Eustachio, P  (2005-07-20)
Created
D'Eustachio, P  (2005-07-20)
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