This reaction has been characterized in vitro using enzyme partially purified from cat liver (Ichiyama et al. 1965). The human event is inferred from the cat one. Neither the cat nor the human protein has been fully purified or sequenced.
Nishizuka, Y, Honjo, T, Hayaishi, O, Ichiyama, A, Kawai, H, Senoh, S, Nakamura, S
aminomuconate-semialdehyde dehydrogenase activity of AM-SHDH [cytosol]
© 2022 Reactome