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SkpA [cytosol]
Stable Identifier
R-DME-174150
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
SKP1, O77430
Locations in the PathwayBrowser for interactor UniProt:Q9V6L9 FBSP1
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G2-G2/M phases (Drosophila melanogaster)
G2/M Transition (Drosophila melanogaster)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Drosophila melanogaster)
Formation of the SCF-FBXL7 complex (Drosophila melanogaster)
SkpA [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O77430 skpA
Gene Names
skpA, Dredd, EG:115C2.4, CG16983, Dmel_CG16983
Reference Genes
BioGPS Gene:31016 skpA
KEGG:dme:Dmel_CG16983 skpA
Monarch:31016 skpA
NCBI Gene:31016 skpA
UCSC:O77430 skpA
Reference Transcript
RefSeq:NM_166861.3 skpA
RefSeq:NM_001038729.3 skpA
RefSeq:NM_166860.3 skpA
RefSeq:NM_166857.3 skpA
RefSeq:NM_001297826.1 skpA
RefSeq:NM_166859.3 skpA
RefSeq:NM_166858.3 skpA
RefSeq:NM_166856.3 skpA
RefSeq:NM_058042.5 skpA
Other Identifiers
153376_at
1625801_s_at
31016
GO:0000278
GO:0002785
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0006511
GO:0016322
GO:0016567
GO:0019005
GO:0030163
GO:0030261
GO:0031146
GO:0032436
GO:0035331
GO:0042023
GO:0043066
GO:0045886
GO:0045931
GO:0046329
GO:0046627
GO:0051298
GO:0060090
GO:0061060
GO:0090090
GO:0097602
GO:0160072
GO:1905088
Participates
as a component of
NEDD8-CRL1 E3 ligase complex [cytosol] (Drosophila melanogaster)
SKP1:CUL1:FBXL5 [cytosol] (Drosophila melanogaster)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Drosophila melanogaster)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Drosophila melanogaster)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Drosophila melanogaster)
SCF E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
CUL1:FBXW11:SKP1 [cytosol] (Drosophila melanogaster)
BTRC:CUL1:SKP1 [cytosol] (Drosophila melanogaster)
as an input of
Formation of the SCF-FBXL7 complex (Drosophila melanogaster)
Other forms of this molecule
SKPA [cytosol]
SkpA [nucleoplasm]
Inferred From
SKP1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001033818.1
,
NP_726690.1
,
NP_001284755.1
,
NP_726692.1
,
NP_726691.1
,
NP_726694.1
,
NP_726693.1
,
NP_477390.1
,
NP_726695.1
FlyBase
FBgn0025637
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VDE3 Q9VDE3
0.83
7
UniProt:Q9V6L9 FBSP1
0.667
3
UniProt:Q9VIW8 Q9VIW8
0.667
4
UniProt:Q9VZF4 FBXW7
0.667
3
UniProt:Q9VNX7
2
FBXL12 [cytosol]
(R-DME-391289-2)
FBXL12 [cytosol]
(R-DME-8862606-2)
0.667
3
UniProt:Q9Y165 Q9Y165
0.641
3
UniProt:Q8SX86 NUTC
0.621
3
UniProt:Q8IGU5 Q8IGU5
0.553
2
UniProt:Q9VED4 Q9VED4
0.553
2
UniProt:Q9W214 Q9W214
0.553
2
UniProt:Q9VKF2 Q9VKF2
0.553
2
UniProt:Q7YZ95
3
Skp2 [cytosol]
(R-DME-975495)
Skp2 [nucleoplasm]
(R-DME-9687073)
Skp2 [nucleoplasm]
(R-DME-975554)
0.553
2
UniProt:Q961T2 Q961T2
0.547
2
UniProt:Q9VM76
6
phospho-Rca1 [nucleoplasm]
(R-DME-163049)
phospho-Rca1 [nucleoplasm]
(R-DME-174220)
phospho-Rca1 [nucleoplasm]
(R-DME-176447)
Rca1 [nucleoplasm]
(R-DME-174060)
phospho-Rca1 [cytosol]
(R-DME-174207)
phospho-Rca1 [cytosol]
(R-DME-177324)
0.547
3
UniProt:Q24311 Cul1
4
LIN19 [cytosol]
(R-DME-206151)
Cul1 [cytosol]
(R-DME-8952519)
Cul1 [nucleoplasm]
(R-DME-187551)
Cul1 [cytosol]
(R-DME-174230)
0.534
3
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