Reactome | H2O2 reduces MetHb

Schema > Reaction > Entries

H2O2 reduces MetHb Show undefined attributes

category	dissociation
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10723121
displayName	H2O2 reduces MetHb
eventOf	[Pathway:R-XTR-9707564] Cytoprotection by HMOX1 - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-9709317] CO binds to free ferrohemoglobin - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-9709360] H2O2 reduces MetHb - Homo sapiens
input	4 × [SimpleEntity:R-ALL-351629] H2O2 [extracellular region] [Complex:R-XTR-2168866] MetHb [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	H2O2 reduces MetHb
output	[Complex:R-XTR-9707672] ferrohemoglobin [extracellular region] 4 × [SimpleEntity:R-ALL-109276] H2O [extracellular region] 2 × [SimpleEntity:R-ALL-352327] O2 [extracellular region]
precedingEvent	[Reaction:R-XTR-9707504] H2O2 oxidises ferrohemoglobin to MetHb - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9709360
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9707564] Cytoprotection by HMOX1
(precedingEvent)	[Reaction:R-XTR-9709317] CO binds to free ferrohemoglobin
(inferredTo)	[Reaction:R-HSA-9709360] H2O2 reduces MetHb