Reactome | eif4g1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-XTR-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] - Xenopus tropicalis [Complex:R-XTR-429977] Translatable mRNA Complex [cytosol] - Xenopus tropicalis [Complex:R-XTR-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] - Xenopus tropicalis [Complex:R-XTR-927845] mRNA Cleaved by SMG6 [cytosol] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-165766] Phosphorylation and activation of eIF4G by activated S6K1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10654195
displayName	eif4g1 [cytosol]
endCoordinate	1599
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol] - Homo sapiens
maxDepth	1
name	eif4g1 EIF4G1 A0A6I8SXK0
producedByEvent	[BlackBoxEvent:R-XTR-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex - Xenopus tropicalis [Reaction:R-XTR-429992] PARN deadenylates mRNA - Xenopus tropicalis [Reaction:R-XTR-429955] CCR4-NOT complex deadenylates mRNA - Xenopus tropicalis
referenceEntity	[ReferenceGeneProduct:uniprot:A0A6I8SXK0] UniProt:A0A6I8SXK0
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-72584
startCoordinate	1

(hasComponent)	[Complex:R-XTR-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] [Complex:R-XTR-927845] mRNA Cleaved by SMG6 [cytosol] [Complex:R-XTR-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] [Complex:R-XTR-927823] mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] [Complex:R-XTR-429977] Translatable mRNA Complex [cytosol] [Complex:R-XTR-429989] Partially Deadenylated mRNA Complex [cytosol] [Complex:R-XTR-72587] eIF4F [cytosol]
(output)	[BlackBoxEvent:R-XTR-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex [Reaction:R-XTR-429992] PARN deadenylates mRNA [Reaction:R-XTR-429955] CCR4-NOT complex deadenylates mRNA
(input)	[Reaction:R-XTR-165766] Phosphorylation and activation of eIF4G by activated S6K1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol]