Reactome | apoa1 [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

apoa1 [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-XTR-8855688] enlarged spherical HDL [extracellular region] - Xenopus tropicalis [Complex:R-XTR-8855688] enlarged spherical HDL [extracellular region] - Xenopus tropicalis [Complex:R-XTR-8855688] enlarged spherical HDL [extracellular region] - Xenopus tropicalis [Complex:R-XTR-8855688] enlarged spherical HDL [extracellular region] - Xenopus tropicalis [Complex:R-XTR-2168878] HPR:APOL1:APOA1:HDL3 [extracellular region] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Xenopus tropicalis [Reaction:R-XTR-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Xenopus tropicalis [Reaction:R-XTR-216727] 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10667732
displayName	apoa1 [extracellular region]
endCoordinate	267
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-174720] APOA1(25-267) [extracellular region] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-XTR-482769] Platelet releasate secretory granule proteins [extracellular region] - Xenopus tropicalis [DefinedSet:R-XTR-2173760] Ligands of MSR1 [extracellular region] - Xenopus tropicalis
name	apoa1 APOA1(25-267) A0A8J0SS71
positivelyRegulates	[PositiveRegulation:10667827] Positive regulation by 'APOA1(25-266) [extracellular region]'
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8J0SS71] UniProt:A0A8J0SS71
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-174720
startCoordinate	25

Referrals

(hasMember)	[DefinedSet:R-XTR-482769] Platelet releasate secretory granule proteins [extracellular region] [DefinedSet:R-XTR-2173760] Ligands of MSR1 [extracellular region]
(hasComponent)	[Complex:R-XTR-8855688] enlarged spherical HDL [extracellular region] [Complex:R-XTR-349645] pre-beta HDL [extracellular region] [Complex:R-XTR-2168878] HPR:APOL1:APOA1:HDL3 [extracellular region] [Complex:R-XTR-216752] discoidal HDL [extracellular region] [Complex:R-XTR-265523] spherical HDL [extracellular region]
(regulator)	[PositiveRegulation:10667827] Positive regulation by 'APOA1(25-266) [extracellular region]'
(input)	[Reaction:R-XTR-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle [Reaction:R-XTR-216727] 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-174720] APOA1(25-267) [extracellular region]

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