Reactome | spherical HDL [extracellular region]

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spherical HDL [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-XTR-266348] spherical HDL:triacylglycerol complex [extracellular region] - Xenopus tropicalis [Complex:R-XTR-8858255] HDLBP:HDL [plasma membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids - Xenopus tropicalis [Reaction:R-XTR-8858252] HDLBP binds HDL - Xenopus tropicalis [Reaction:R-XTR-349404] CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex - Xenopus tropicalis [Reaction:R-XTR-266315] LCAT + spherical HDL <=> LCAT:spherical HDL complex - Xenopus tropicalis [Reaction:R-XTR-266328] CETP-mediated lipid exchange: spherical HDL gains triacylglycerol - Xenopus tropicalis [Reaction:R-XTR-349637] spherical HDL and SR-BI receptor form a complex at the cell surface - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10668044
displayName	spherical HDL [extracellular region]
hasComponent	4 × [EntityWithAccessionedSequence:R-XTR-174720] apoa1 [extracellular region] 160 × [SimpleEntity:R-ALL-171076] CHEST [extracellular region] 40 × [SimpleEntity:R-ALL-171149] CHOL [extracellular region] 140 × [SimpleEntity:R-ALL-171066] PL [extracellular region] 20 × [SimpleEntity:R-ALL-171126] TAGs [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-265523] spherical HDL [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-XTR-2197637] Ligands of SCARB1 [extracellular region] - Xenopus tropicalis [DefinedSet:R-XTR-2187232] Ligands of CD36 [extracellular region] - Xenopus tropicalis
name	spherical HDL
producedByEvent	[Reaction:R-XTR-266310] LCAT:spherical HDL complex <=> LCAT + spherical HDL - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-265523
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-XTR-8858252] HDLBP binds HDL [Reaction:R-XTR-266299] Spherical HDL binds membrane-associated free cholesterol and phospholipids [Reaction:R-XTR-349404] CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex [Reaction:R-XTR-266315] LCAT + spherical HDL <=> LCAT:spherical HDL complex [Reaction:R-XTR-266328] CETP-mediated lipid exchange: spherical HDL gains triacylglycerol [Reaction:R-XTR-349637] spherical HDL and SR-BI receptor form a complex at the cell surface
(hasComponent)	[Complex:R-XTR-8858255] HDLBP:HDL [plasma membrane] [Complex:R-XTR-349410] CETP:spherical HDL:torcetrapib complex [extracellular region] [Complex:R-XTR-266308] LCAT:spherical HDL complex [extracellular region] [Complex:R-XTR-266348] spherical HDL:triacylglycerol complex [extracellular region]
(output)	[Reaction:R-XTR-266310] LCAT:spherical HDL complex <=> LCAT + spherical HDL
(hasMember)	[DefinedSet:R-XTR-2197637] Ligands of SCARB1 [extracellular region] [DefinedSet:R-XTR-2187232] Ligands of CD36 [extracellular region]
(inferredTo)	[Complex:R-HSA-265523] spherical HDL [extracellular region]

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