Reactome | LYN phosphorylates CD22

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LYN phosphorylates CD22 Show undefined attributes

catalystActivity	[CatalystActivity:10521673] protein tyrosine kinase activity of MyrG2-PalmC3-LYN [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10521675
displayName	LYN phosphorylates CD22
eventOf	[Pathway:R-SSC-5690714] CD22 mediated BCR regulation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-5690701] SHP1 binds p-CD22 - Sus scrofa
inferredFrom	[Reaction:R-HSA-5690702] LYN phosphorylates CD22 - Homo sapiens
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-5690660] CD22:Antigen:p-BCR [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	LYN phosphorylates CD22
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-5690689] p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane]
precedingEvent	[Reaction:R-SSC-5690740] CD22 binds B-cell receptor - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5690702
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5690714] CD22 mediated BCR regulation
(precedingEvent)	[Reaction:R-SSC-5690701] SHP1 binds p-CD22
(inferredTo)	[Reaction:R-HSA-5690702] LYN phosphorylates CD22

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