Reactome | CD22 mediated BCR regulation

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10558391
displayName	CD22 mediated BCR regulation
eventOf	[Pathway:R-SSC-983705] Signaling by the B Cell Receptor (BCR) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Polymerisation:R-SSC-5690669] CD22 binds itself to form homo-oligomers - Sus scrofa [Reaction:R-SSC-5690740] CD22 binds B-cell receptor - Sus scrofa [Reaction:R-SSC-5690702] LYN phosphorylates CD22 - Sus scrofa [Reaction:R-SSC-5690701] SHP1 binds p-CD22 - Sus scrofa
inferredFrom	[Pathway:R-HSA-5690714] CD22 mediated BCR regulation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CD22 mediated BCR regulation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-5690714
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-983705] Signaling by the B Cell Receptor (BCR)
(inferredTo)	[Pathway:R-HSA-5690714] CD22 mediated BCR regulation

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