Reactome | SHP1 binds p-CD22

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10521666
displayName	SHP1 binds p-CD22
eventOf	[Pathway:R-SSC-5690714] CD22 mediated BCR regulation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5690701] SHP1 binds p-CD22 - Homo sapiens
input	[Complex:R-SSC-5690689] p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane] [EntityWithAccessionedSequence:R-SSC-197938] PTPN6 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SHP1 binds p-CD22
output	[Complex:R-SSC-5690677] PTPN6:p-Y762,807,822-CD22:Antigen:p-BCR [plasma membrane]
precedingEvent	[Reaction:R-SSC-5690702] LYN phosphorylates CD22 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5690701
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-5690714] CD22 mediated BCR regulation
(inferredTo)	[Reaction:R-HSA-5690701] SHP1 binds p-CD22