Reactome | Inactivation, recovery and regulation of the phototransduction cascade

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Inactivation, recovery and regulation of the phototransduction cascade Show undefined attributes

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10555827
displayName	Inactivation, recovery and regulation of the phototransduction cascade
eventOf	[Pathway:R-SSC-2514856] The phototransduction cascade - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:260187] regulation of opsin-mediated signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-2534096] METAP1/2 demethylates GNAT1 - Sus scrofa [Reaction:R-SSC-2534087] NMT1/2 transfer MYS to GNAT1 - Sus scrofa [Reaction:R-SSC-2581474] GRK1,4,7 phosphorylate MII to p-MII - Sus scrofa [Reaction:R-SSC-2632521] at-retinyl is hydrolysed from p-MII:SAG to release atRAL - Sus scrofa [Reaction:R-SSC-74948] PP2A dephosphorylates p-RHO to RHO - Sus scrofa [Reaction:R-SSC-2584246] GNAT1-GTP hydrolyses its bound GTP to GDP - Sus scrofa [Reaction:R-SSC-2586748] GUCA binds Ca2+ to form GUCA:Ca2+ - Sus scrofa [Reaction:R-SSC-74885] GUCYs converts GTP to cGMP - Sus scrofa [Reaction:R-SSC-74031] cGMP binds CNG channel to form cGMP:CNG channel - Sus scrofa
inferredFrom	[Pathway:R-HSA-2514859] Inactivation, recovery and regulation of the phototransduction cascade - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Inactivation, recovery and regulation of the phototransduction cascade
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-2514859
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-2514856] The phototransduction cascade
(inferredTo)	[Pathway:R-HSA-2514859] Inactivation, recovery and regulation of the phototransduction cascade

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