Reactome | Klotho bound to FGF23 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-SSC-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - Sus scrofa [Complex:R-SSC-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-190268] FGFR1c binds to Klotho-bound FGF23 - Sus scrofa [Reaction:R-SSC-190268] FGFR1c binds to Klotho-bound FGF23 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10453935
displayName	Klotho bound to FGF23 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-SSC-189891] FGF23 [extracellular region] [Complex:R-SSC-190309] Klotho homodimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-190208] Klotho bound to FGF23 [plasma membrane] - Homo sapiens
maxDepth	6
name	Klotho bound to FGF23
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-190208
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-190268] FGFR1c binds to Klotho-bound FGF23
(hasComponent)	[Complex:R-SSC-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] [Complex:R-SSC-500333] Activated FGFR1c bound to FGF23:Klotho [plasma membrane]
(inferredTo)	[Complex:R-HSA-190208] Klotho bound to FGF23 [plasma membrane]