Reactome | FGF23 bound to Klotho and FGFR1c [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10331367] protein tyrosine kinase activity of FGF23 bound to Klotho and FGFR1c [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-SSC-191062] Autocatalytic phosphorylation of Klotho-bound FGFR1c - Sus scrofa
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10331084
displayName	FGF23 bound to Klotho and FGFR1c [plasma membrane]
hasComponent	[Complex:R-SSC-190222] FGFR1c homodimer [plasma membrane] [SimpleEntity:R-ALL-190915] HS [extracellular region] 2 × [Complex:R-SSC-190208] Klotho bound to FGF23 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane] - Homo sapiens
name	FGF23 bound to Klotho and FGFR1c
producedByEvent	[Reaction:R-SSC-190268] FGFR1c binds to Klotho-bound FGF23 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-190218
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-191062] Autocatalytic phosphorylation of Klotho-bound FGFR1c
(physicalEntity)	[CatalystActivity:10331367] protein tyrosine kinase activity of FGF23 bound to Klotho and FGFR1c [plasma membrane]
(output)	[Reaction:R-SSC-190268] FGFR1c binds to Klotho-bound FGF23
(inferredTo)	[Complex:R-HSA-190218] FGF23 bound to Klotho and FGFR1c [plasma membrane]