Reactome | Inactivation of APC/C via CDC20 sequestration

Schema > Reaction > Entries

Inactivation of APC/C via CDC20 sequestration Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10456947
displayName	Inactivation of APC/C via CDC20 sequestration
eventOf	[Pathway:R-SSC-141405] Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-141429] Inactivation of APC/C via CDC20 sequestration - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-141412] CDC20 [cytosol] [EntityWithAccessionedSequence:R-SSC-141400] MAD2L1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Inactivation of APC/C via CDC20 sequestration
output	[Complex:R-SSC-141408] MAD2*CDC20 complex [cytosol]
precedingEvent	[Reaction:R-SSC-141439] Release of activated MAD2 from kinetochores - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-141429
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-141405] Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
(inferredTo)	[Reaction:R-HSA-141429] Inactivation of APC/C via CDC20 sequestration

Cite Us!