Reactome | Gfap binds Lamp2 multimer

Schema > Reaction > Entries

authored	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
category	binding
compartment	[Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9625192] Varusai, Thawfeek, 2018-10-19
dbId	9625183
displayName	Gfap binds Lamp2 multimer
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
followingEvent	[Reaction:R-RNO-9625173] Unfolded substrate in Lamp2 multimeric complex binds Hspa8 - Rattus norvegicus
input	[EntityWithAccessionedSequence:R-RNO-9625200] Gfap [lysosomal membrane] [Polymer:R-RNO-9624151] Lamp2 multimer complex [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9624149] Identification of regulators of chaperone-mediated autophagy [LiteratureReference:9625184] Chaperone-mediated autophagy at a glance
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Gfap binds Lamp2 multimer
orthologousEvent	[Reaction:R-HSA-9625197] GFAP binds LAMP2a multimer - Homo sapiens
output	[Complex:R-RNO-9625167] Lamp2 multimer complex: Gfap [lysosomal membrane]
precedingEvent	[Polymerisation:R-RNO-9624154] Substrate:Lamp2a:Hsp90 polymerizes - Rattus norvegicus
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9625183
summation	[Summation:9625198] Intracellular proteins are targeted for proteolytic degradat...

(precedingEvent)

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