Reactome | GFAP binds LAMP2a multimer

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GFAP binds LAMP2a multimer Show undefined attributes

authored	[InstanceEdit:9637871] Varusai, Thawfeek, 2019-02-21
category	binding
compartment	[Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9625192] Varusai, Thawfeek, 2018-10-19
dbId	9625197
displayName	GFAP binds LAMP2a multimer
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
eventOf	[Pathway:R-HSA-9613829] Chaperone Mediated Autophagy - Homo sapiens
followingEvent	[Reaction:R-HSA-9625196] Unfolded substrate in LAMP2a multimeric complex binds HSPA8 - Homo sapiens
inferredFrom	[Reaction:R-RNO-9625183] Gfap binds Lamp2 multimer - Rattus norvegicus
input	[EntityWithAccessionedSequence:R-HSA-9625195] GFAP [lysosomal membrane] [Polymer:R-HSA-9624156] LAMP2a multimer complex [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9625184] Chaperone-mediated autophagy at a glance [LiteratureReference:9624149] Identification of regulators of chaperone-mediated autophagy
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GFAP binds LAMP2a multimer
output	[Complex:R-HSA-9625181] LAMP2a multimer complex:GFAP [lysosomal membrane]
precedingEvent	[Polymerisation:R-HSA-9624158] Substrate:LAMP2a:HSP90 polymerizes - Homo sapiens
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9625197
summation	[Summation:9625185] Intracellular proteins are targeted for proteolytic degradat...

Referrals

(hasEvent)	[Pathway:R-HSA-9613829] Chaperone Mediated Autophagy
(precedingEvent)	[Reaction:R-HSA-9625196] Unfolded substrate in LAMP2a multimeric complex binds HSPA8
(inferredTo)	[Reaction:R-RNO-9625183] Gfap binds Lamp2 multimer

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