Reactome | Substrate:Lamp2a:Hsp90 polymerizes

Schema > Polymerisation > Entries

authored	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
category	transition
compartment	[Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9624150] Varusai, Thawfeek, 2018-10-08
dbId	9624154
displayName	Substrate:Lamp2a:Hsp90 polymerizes
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
followingEvent	[Reaction:R-RNO-9625183] Gfap binds Lamp2 multimer - Rattus norvegicus
input	[Complex:R-RNO-9622842] Rnase1:Lamp2:Hsp90 [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9622837] The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane [LiteratureReference:9624149] Identification of regulators of chaperone-mediated autophagy
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Substrate:Lamp2a:Hsp90 polymerizes
orthologousEvent	[Polymerisation:R-HSA-9624158] Substrate:LAMP2a:HSP90 polymerizes - Homo sapiens
output	[Polymer:R-RNO-9624151] Lamp2 multimer complex [lysosomal membrane]
precedingEvent	[Reaction:R-RNO-9622851] Substrate:Lamp2a binds Hsp90 - Rattus norvegicus
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Polymerisation
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9624154
summation	[Summation:9624155] Intracellular proteins are targeted for proteolytic degradat...

(precedingEvent)

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