Reactome | Substrate:Lamp2a binds Hsp90

Schema > Reaction > Entries

authored	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
category	binding
compartment	[Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:9622834] Varusai, Thawfeek, 2018-10-02
dbId	9622851
displayName	Substrate:Lamp2a binds Hsp90
edited	[InstanceEdit:9667290] Varusai, Thawfeek, 2019-11-08
followingEvent	[Polymerisation:R-RNO-9624154] Substrate:Lamp2a:Hsp90 polymerizes - Rattus norvegicus
input	[DefinedSet:R-RNO-9622830] Hsp90aa1, Hsp90ab1 [lysosomal lumen] [Complex:R-RNO-9622844] Rnase1:Lamp2 [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9622837] The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane [LiteratureReference:9622849] The coming of age of chaperone-mediated autophagy
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Substrate:Lamp2a binds Hsp90
orthologousEvent	[Reaction:R-HSA-9622831] Substrate:LAMP2a binds HSP90 - Homo sapiens
output	[Complex:R-RNO-9622842] Rnase1:Lamp2:Hsp90 [lysosomal membrane]
precedingEvent	[Reaction:R-RNO-9622832] Hspa8 dissociates from Lamp2a-bound substrate - Rattus norvegicus
releaseDate	2019-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9637993] Metzakopian, Emmanouil, 2019-02-22
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9622851
summation	[Summation:9622833] Heat shock cognate 71 kDa protein (HSPA8) translocates subst...

(precedingEvent)

Cite Us!