Reactome | phospho-p-S400,T290-MAP3K8 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5684265] NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10142099
displayName	phospho-p-S400,T290-MAP3K8 [cytosol]
endCoordinate	467
hasModifiedResidue	[ModifiedResidue:10142097] O-phospho-L-threonine at 290 (in Homo sapiens) [ModifiedResidue:10134813] O-phospho-L-serine at 400 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5684259] p-S400,T290-MAP3K8 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-p-S400,T290-MAP3K8 Q63562
producedByEvent	[BlackBoxEvent:R-RNO-5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:Q63562] UniProt:Q63562 Map3k8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5684259
startCoordinate	1

(output)	[BlackBoxEvent:R-RNO-5684273] 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105
(hasComponent)	[Complex:R-RNO-5684265] NFKB1:p-T290-MAP3K8:TNIP2 [cytosol] [Complex:R-RNO-5684268] p-S927,S932-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol] [Complex:R-RNO-5684242] 3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5684259] p-S400,T290-MAP3K8 [cytosol]

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