Reactome | Amino acid transport across the plasma membrane

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Amino acid transport across the plasma membrane Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223483
displayName	Amino acid transport across the plasma membrane
eventOf	[Pathway:R-RNO-9958863] SLC-mediated transport of amino acids - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20641] amino acid transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-352158] SLC16A10-mediated uptake of aromatic amino acids - Rattus norvegicus [Reaction:R-RNO-352119] SLC38A1 (ATA1)-mediated uptake of neutral amino acids - Rattus norvegicus [Reaction:R-RNO-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Rattus norvegicus [Reaction:R-RNO-352174] SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine - Rattus norvegicus [Reaction:R-RNO-352136] SLC38A4 (ATA3)-mediated uptake of arginine and lysine - Rattus norvegicus [Reaction:R-RNO-352182] SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine - Rattus norvegicus [Reaction:R-RNO-352103] SLC43A1 (LAT3)-mediated uptake of large neutral amino acids - Rattus norvegicus [Reaction:R-RNO-352107] SLC43A2 (LAT4)-mediated uptake of large neutral amino acids - Rattus norvegicus [Reaction:R-RNO-352029] SLC6A12 (BGT-1)-mediated uptake of GABA and betaine - Rattus norvegicus [Reaction:R-RNO-352059] SLC6A15-mediated amino acid uptake - Rattus norvegicus [Reaction:R-RNO-352052] SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-351987] SLC6A6-mediated uptake of taurine and beta-alanine - Rattus norvegicus [Reaction:R-RNO-352232] SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-352191] SLC7A8-mediated uptake of neutral amino acids - Rattus norvegicus [Reaction:R-RNO-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Rattus norvegicus [Reaction:R-RNO-352354] SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine - Rattus norvegicus [Reaction:R-RNO-352347] SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine - Rattus norvegicus [Reaction:R-RNO-352371] SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine - Rattus norvegicus [Reaction:R-RNO-352379] SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane - Rattus norvegicus [Reaction:R-RNO-352385] SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane - Rattus norvegicus [Reaction:R-RNO-375417] SLC36A1-mediated uptake of glycine, proline, and alanine - Rattus norvegicus [Reaction:R-RNO-375405] SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-8870354] SLC36A4 transports extracellular L-Pro to the cytosol - Rattus norvegicus [Reaction:R-RNO-375487] SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-375473] SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-RNO-375776] SLC7A1 (CAT-1)-mediated uptake of cationic amino acids - Rattus norvegicus [Reaction:R-RNO-375770] SLC7A3 (CAT-3)-mediated uptake of cationic amino acids - Rattus norvegicus [Reaction:R-RNO-376200] SLC7A10-mediated uptake of small neutral amino acids - Rattus norvegicus [Reaction:R-RNO-378513] SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate - Rattus norvegicus [Reaction:R-RNO-379426] SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine - Rattus norvegicus [Reaction:R-RNO-379415] SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane - Rattus norvegicus [Reaction:R-RNO-379432] SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu - Rattus norvegicus [BlackBoxEvent:R-RNO-8959781] SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Amino acid transport across the plasma membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-352230
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9958863] SLC-mediated transport of amino acids
(inferredTo)	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane

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