Reactome | Ptges3 [cytosol]

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Ptges3 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-9725882] HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] - Rattus norvegicus [Complex:R-RNO-9725882] HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] - Rattus norvegicus [Complex:R-RNO-9706851] HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] - Rattus norvegicus [Complex:R-RNO-9706851] HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] - Rattus norvegicus [Complex:R-RNO-8936844] AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] - Rattus norvegicus [Complex:R-RNO-9705909] HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] - Rattus norvegicus [Complex:R-RNO-9705909] HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5618098] p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein - Rattus norvegicus [Reaction:R-RNO-5618098] p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein - Rattus norvegicus [Reaction:R-RNO-5618110] p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein - Rattus norvegicus [Reaction:R-RNO-5618110] p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10129120
displayName	Ptges3 [cytosol]
endCoordinate	160
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-265269] PTGES3 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-8864254] PTGES2(88-377), PTGES3 [cytosol] - Rattus norvegicus
name	Ptges3 PTGES3 P83868
producedByEvent	[Reaction:R-RNO-5324632] Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates - Rattus norvegicus [Reaction:R-RNO-5324632] Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates - Rattus norvegicus [Reaction:R-RNO-3371586] Dissociation of cytosolic HSF1:HSP90 complex - Rattus norvegicus [Reaction:R-RNO-3371586] Dissociation of cytosolic HSF1:HSP90 complex - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:P83868] UniProt:P83868
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-265269
startCoordinate	1

Referrals

(hasMember)	[DefinedSet:R-RNO-8864254] PTGES2(88-377), PTGES3 [cytosol]
(hasComponent)	[Complex:R-RNO-8936844] AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] [Complex:R-RNO-9678833] HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] [Complex:R-RNO-9725882] HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] [Complex:R-RNO-9605366] HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] [Complex:R-RNO-9705910] HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] [Complex:R-RNO-9705909] HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] [Complex:R-RNO-9725883] HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] [Complex:R-RNO-5618074] HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] [Complex:R-RNO-5618101] HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] [Complex:R-RNO-9725884] HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] [Complex:R-RNO-8948980] HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] [Complex:R-RNO-9706851] HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] [Complex:R-RNO-9705922] HSP90:ATP:FKBP4:PTGES3:AR [cytosol] [Complex:R-RNO-9725890] HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] [Complex:R-RNO-5324677] HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] [Complex:R-RNO-4793919] HSF1:HSP90:PTGES3 [cytosol]
(input)	[Reaction:R-RNO-5618098] p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein [Reaction:R-RNO-5618110] p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein
(output)	[Reaction:R-RNO-5324632] Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates [Reaction:R-RNO-3371586] Dissociation of cytosolic HSF1:HSP90 complex
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-265269] PTGES3 [cytosol]

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