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Ptges3 [cytosol]
Stable Identifier
R-RNO-265269
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
PTGES3, P83868
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to heat stress (Rattus norvegicus)
HSF1 activation (Rattus norvegicus)
Dissociation of cytosolic HSF1:HSP90 complex (Rattus norvegicus)
HSF1:HSP90:PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Rattus norvegicus)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Rattus norvegicus)
AR binds AR agonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
AR binds AR antagonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Androgens binds AR (in the HSP90 chaperone complex) (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C1 binds NR3C1 agonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C2 binds NR3C2 antagonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C2:NR3C2 antagonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C2 binds fludrocortisone (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C2:fludrocortisone [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
P4 bind PGR (in the HSP90 chaperone complex) (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
PGR binds PGR agonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
PGR:PGR agonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
PGR binds PGR antagonists (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
PGR:PGR antagonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Aryl hydrocarbon receptor signalling (Rattus norvegicus)
AHR:2xHSP90:AIP:PTGES3 binds TCDD (Rattus norvegicus)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Rattus norvegicus)
AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonic acid metabolism (Rattus norvegicus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
Prostaglandin E synthase isomerizes PGH2 to PGE2 (Rattus norvegicus)
PTGES2(88-377), PTGES3 [cytosol] (Rattus norvegicus)
Ptges3 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P83868
Gene Names
Ptges3
Reference Genes
BioGPS Gene:362809 Ptges3
ENSEMBL:ENSRNOG00000002642
ENSEMBL:ENSRNOG00055013521
ENSEMBL:ENSRNOG00060023883
ENSEMBL:ENSRNOG00065013256
KEGG Gene (Rattus norvegicus):362809 Ptges3
Monarch:362809 Ptges3
NCBI Gene:362809 Ptges3
UCSC:P83868 Ptges3
Reference Transcript
RefSeq:NM_001130989.1 Ptges3
Participates
as a member of
PTGES2(88-377), PTGES3 [cytosol] (Rattus norvegicus)
as a component of
AHR:2xHSP90AB1:AIP:PTGES3 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 agonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1:NR3C1 ligands [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C1 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:AR agonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:Androgens [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR:P4 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP5:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:nascent protein: [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2 [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR:AR antagonists [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:AR [cytosol] (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] (Rattus norvegicus)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Rattus norvegicus)
HSF1:HSP90:PTGES3 [cytosol] (Rattus norvegicus)
as an input of
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Rattus norvegicus)
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Rattus norvegicus)
as an output of
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Rattus norvegicus)
Dissociation of cytosolic HSF1:HSP90 complex (Rattus norvegicus)
Other forms of this molecule
Ptges3 [nucleoplasm]
Inferred From
PTGES3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001124461.1
PRO
P83868
RGD
1561913
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