Reactome | p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]

Schema > Complex > Entries

p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-2130280] RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-2130279] Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex - Rattus norvegicus [Reaction:R-RNO-195280] Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10122955
displayName	p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-RNO-1504189] Amer1 [cytosol] [EntityWithAccessionedSequence:R-RNO-195263] CSNK1A1 [cytosol] [EntityWithAccessionedSequence:R-RNO-198619] Glycogen synthase kinase-3 beta [cytosol] [EntityWithAccessionedSequence:R-RNO-3009421] phospho-Apc [cytosol] [EntityWithAccessionedSequence:R-RNO-206040] phospho-Axin1 [cytosol] [EntityWithAccessionedSequence:R-RNO-8942374] phospho-Ctnnb1 [cytosol] [Complex:R-RNO-196206] PP2A [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-195322] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] - Homo sapiens [Complex:R-HSA-195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] - Homo sapiens
maxDepth	4
name	p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex
producedByEvent	[Reaction:R-RNO-195280] Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex - Rattus norvegicus [Reaction:R-RNO-195275] Phosphorylation of APC component of the destruction complex - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-195297
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-2130279] Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex [Reaction:R-RNO-195280] Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex
(output)	[Reaction:R-RNO-195280] Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex [Reaction:R-RNO-195275] Phosphorylation of APC component of the destruction complex
(hasComponent)	[Complex:R-RNO-2130280] RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol]
(inferredTo)	[Complex:R-HSA-195322] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] [Complex:R-HSA-195297] p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]

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