Reactome | Dtx4 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-RNO-1604454] DTX [cytosol] - Rattus norvegicus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-8948707] NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-3249392] NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10159214
displayName	Dtx4 [cytosol]
endCoordinate	619
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-1604439] DTX4 [cytosol] - Homo sapiens
maxDepth	1
name	Dtx4 DTX4 A0A0G2K048
producedByEvent	[Reaction:R-RNO-8948709] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:A0A0G2K048] UniProt:A0A0G2K048
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1604439
startCoordinate	1

(output)	[Reaction:R-RNO-8948709] DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3
(activeUnit)	[CatalystActivity:10205218] ubiquitin-protein transferase activity of NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane]
(input)	[Reaction:R-RNO-3249392] NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3
(hasComponent)	[Complex:R-RNO-8948707] NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane]
(hasCandidate)	[CandidateSet:R-RNO-1604454] DTX [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-1604439] DTX4 [cytosol]

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