Reactome | ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-1918095] CUL5 mediates ubiquitination of ERBB2 - Rattus norvegicus [Reaction:R-RNO-1918092] CHIP (STUB1) mediates ubiquitination of ERBB2 - Rattus norvegicus [Reaction:R-RNO-9652264] ERBB2 binds TKIs - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10159342
displayName	ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]
hasComponent	[Complex:R-RNO-1225828] CDC37 [cytosol] [EntityWithAccessionedSequence:R-RNO-372889] ERBB2 [plasma membrane] [GenomeEncodedEntity:R-RNO-1358718] Ghost homologue of ERBIN [plasma membrane] [Complex:R-RNO-1221657] HSP90 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-1227970] ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] - Homo sapiens
maxDepth	3
name	ERBB2:ERBIN:HSP90:CDC37
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1227970
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-1918095] CUL5 mediates ubiquitination of ERBB2 [Reaction:R-RNO-1918092] CHIP (STUB1) mediates ubiquitination of ERBB2 [Reaction:R-RNO-9652264] ERBB2 binds TKIs
(inferredTo)	[Complex:R-HSA-1227970] ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]