Reactome | Jak2 [cytosol]

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Jak2 [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-RNO-8987151] JAK2, JAK3 [cytosol] - Rattus norvegicus [CandidateSet:R-RNO-5672734] RAF activating kinases [plasma membrane] - Rattus norvegicus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Rattus norvegicus [Complex:R-RNO-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Rattus norvegicus [Complex:R-RNO-8950151] IL23R:JAK2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-1433451] JAK2 binds to p-KIT - Rattus norvegicus [Reaction:R-RNO-1433451] JAK2 binds to p-KIT - Rattus norvegicus [Reaction:R-RNO-1366606] Prlr associates with Jak2 - Rattus norvegicus [Reaction:R-RNO-982792] Growth hormone receptor binds JAK2 - Rattus norvegicus [Reaction:R-RNO-6785898] IL4R binds JAK2 - Rattus norvegicus
created	[InstanceEdit:1168888] Jupe, S, 2011-01-10
dbId	1168889
displayName	Jak2 [cytosol]
endCoordinate	1132
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-210620] JAK2 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[CandidateSet:R-RNO-1067656] JAK1, JAK2, (TYK2) [cytosol] - Rattus norvegicus
name	Jak2 Tyrosine-protein kinase JAK2 JAK2_RAT Jak2
referenceEntity	[ReferenceGeneProduct:uniprot:Q62689] UniProt:Q62689 Jak2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1168889
startCoordinate	1

Referrals

(hasComponent)	[Complex:R-RNO-8950151] IL23R:JAK2 [plasma membrane] [Complex:R-RNO-8950039] IL12RB2:JAK2 [plasma membrane] [Complex:R-RNO-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] [Complex:R-RNO-914033] p(Y593)-Bc:JAK2 [plasma membrane] [Complex:R-RNO-914173] p-S585-IL3RB:JAK2 [plasma membrane] [Complex:R-RNO-9006298] EPOR:JAK2:LYN:IRS2 [plasma membrane] [Complex:R-RNO-1369107] Prlr:Jak2 [plasma membrane] [Complex:R-RNO-1370506] p(S349)-PRLR:JAK2 [plasma membrane] [Complex:R-RNO-1302663] PRLR:JAK2 [plasma membrane] [Complex:R-RNO-982774] Growth Hormone Receptor:JAK2 [plasma membrane] [Complex:R-RNO-6785800] IL4R:JAK2 [plasma membrane] [Complex:R-RNO-6786120] p-Y-IL4R:JAK2 [plasma membrane] [Complex:R-RNO-873808] IFNGR2:JAK2 [plasma membrane] [Complex:R-RNO-879945] IL3RB:JAK2 [plasma membrane] [Complex:R-RNO-912316] pY593,Y628-IL3RB:JAK2 [plasma membrane]
(hasCandidate)	[CandidateSet:R-RNO-8987151] JAK2, JAK3 [cytosol] [CandidateSet:R-RNO-5672734] RAF activating kinases [plasma membrane]
(activeUnit)	[CatalystActivity:10153363] protein tyrosine kinase activity of JAK2:SFKS:p-KIT complex [plasma membrane] [CatalystActivity:10144418] non-membrane spanning protein tyrosine kinase activity of High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane] [CatalystActivity:10144141] protein tyrosine kinase activity of IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane]
(input)	[Reaction:R-RNO-1433451] JAK2 binds to p-KIT [Reaction:R-RNO-1366606] Prlr associates with Jak2 [Reaction:R-RNO-982792] Growth hormone receptor binds JAK2 [Reaction:R-RNO-6785898] IL4R binds JAK2
(hasMember)	[CandidateSet:R-RNO-1067656] JAK1, JAK2, (TYK2) [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-210620] JAK2 [cytosol]

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