Reactome | RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160

Schema > Reaction > Entries

authored	[InstanceEdit:9668537] Orlic-Milacic, Marija, 2019-11-26
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9616175] Orlic-Milacic, Marija, 2018-08-09
dbId	9616176
displayName	RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160
edited	[InstanceEdit:9668537] Orlic-Milacic, Marija, 2019-11-26
input	[Complex:R-XLA-9616164] kpnb1:nup107-160 complex [cytosol] [Complex:R-HSA-180686] RAN:GTP [cytosol]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9615919] Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160
orthologousEvent	[Reaction:R-HSA-9615945] RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160 - Homo sapiens
output	[Complex:R-XLA-9616145] Nup107-160 complex [cytosol] [Complex:R-NUL-9616202] RAN:GTP:kpnb1 [cytosol]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9667932] Gerace, Larry, 2019-11-07
schemaClass	Reaction
species	[Species:51320] Xenopus laevis [Species:48887] Homo sapiens
stId	R-NUL-9616176
summation	[Summation:9616180] Recombinant human RAN:GTP binds to Xenopus importin beta (kp...

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