RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160

Stable Identifier
R-NUL-9616176
Type
Reaction [transition]
Species
Xenopus laevis
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RAN:GTP binds importin beta associated with nup107-160 and displaces nup107-160
Recombinant human RAN:GTP binds to Xenopus importin beta (kpnb1) associated with the Xenopus nup107-160 complex and displaces nup107-160 (Lau et al. 2009).
Literature References
PubMed ID Title Journal Year
19641022 Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly

Lau, CK, Delmar, VA, Chan, RC, Phung, Q, Bernis, C, Fichtman, B, Rasala, BA, Forbes, DJ

Mol. Biol. Cell 2009
Participants
Input
Output
Orthologous Events
RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160 (Homo sapiens)
Authored
Orlic-Milacic, M  (2019-11-26)
Reviewed
Gerace, L  (2019-11-07)
Created
Orlic-Milacic, M  (2018-08-09)
Cite Us!