Reactome | Fbxl21:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2

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Fbxl21:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2 Show undefined attributes

authored	[InstanceEdit:9932581] May, Bruce, 2024-12-20
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9932863] May, Bruce, 2024-12-20
dbId	9932872
deleted	[Deleted:9939520] Deletion of instance: 517959 [Deleted:9032442] Deletion of instance: 508751 [Deleted:9032440] Deletion of instance: 5334727
displayName	Fbxl21:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2
edited	[InstanceEdit:9932581] May, Bruce, 2024-12-20
input	[Complex:R-MMU-9932858] Fbxl21:Cul1:Skp1:Rbx1:p-S-Cry1,2 [cytosol] 3 × [Complex:R-MMU-9932867] Ub:Ube2d1 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9932516] Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm [LiteratureReference:9932876] FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes
maxDepth	1
modified	[InstanceEdit:9938697] May, Bruce, 2025-02-18
name	Fbxl21:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2
orthologousEvent	[BlackBoxEvent:R-HSA-9932859] FBXL21:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2 - Homo sapiens
output	[Complex:R-MMU-9932873] Fbxl21:Cul1:Skp1:Rbx1 [cytosol] [DefinedSet:R-MMU-9933311] K48polyUb-K107,p-S-Cry1,K48polyUb-K125,p-S-Cry2 [cytosol] 3 × [EntityWithAccessionedSequence:R-MMU-9932888] Ube2d1 [cytosol]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9932872
summation	[Summation:9933313] The SCF ubiquitin E3 ligase complex Fbxl21:Cul1:Skp1:Rbx1 po...

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