Reactome | RBBP8 homotetramer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-5687663] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8 [nucleoplasm] - Mus musculus [Complex:R-MMU-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5687465] MRN complex binds RBBP8 - Mus musculus [Reaction:R-MMU-5684081] MRN complex binds CDK2 and RBBP8 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10060719
displayName	RBBP8 homotetramer [nucleoplasm]
hasComponent	4 × [EntityWithAccessionedSequence:R-MMU-912399] Rbbp8 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5684097] RBBP8 homotetramer [nucleoplasm] - Homo sapiens
maxDepth	2
name	RBBP8 homotetramer
producedByEvent	[BlackBoxEvent:R-MMU-5685953] SIRT6 deacetylates RBBP8 - Mus musculus [Reaction:R-MMU-5687675] LIG3 ligates remaining SSBs in MMEJ - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5684097
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-MMU-5687675] LIG3 ligates remaining SSBs in MMEJ [BlackBoxEvent:R-MMU-5685953] SIRT6 deacetylates RBBP8
(hasComponent)	[Complex:R-MMU-5687663] Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-5687468] DNA DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-5687460] Microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-5687488] Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-5687644] Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8 [nucleoplasm] [Complex:R-MMU-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
(input)	[Reaction:R-MMU-5687465] MRN complex binds RBBP8 [Reaction:R-MMU-5684081] MRN complex binds CDK2 and RBBP8
(inferredTo)	[Complex:R-HSA-5684097] RBBP8 homotetramer [nucleoplasm]