Reactome | DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10060732] protein serine/threonine kinase activity of DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-MMU-5684096] CDK2 phosphorylates RBBP8 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10060721
displayName	DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
hasComponent	[Complex:R-MMU-187952] CCNA:p-T160-CDK2 [nucleoplasm] [Complex:R-MMU-5682162] DNA DSB:p-MRN:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm] [Complex:R-MMU-5684097] RBBP8 homotetramer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] - Homo sapiens
maxDepth	5
name	DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8
producedByEvent	[Reaction:R-MMU-5684081] MRN complex binds CDK2 and RBBP8 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5684094
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(inferredTo)	[Complex:R-HSA-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
(output)	[Reaction:R-MMU-5684081] MRN complex binds CDK2 and RBBP8
(input)	[Reaction:R-MMU-5684096] CDK2 phosphorylates RBBP8
(physicalEntity)	[CatalystActivity:10060732] protein serine/threonine kinase activity of DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]

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