Reactome | Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10058275] ubiquitin protein ligase activity of Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-5654363] Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5654684] CBL ubiquitinates FRS2 and FGFR4 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10058272
displayName	Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
hasComponent	[Complex:R-MMU-5654330] Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] [Complex:R-MMU-182964] p-Y371-CBL:GRB2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Homo sapiens
maxDepth	7
name	Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2
producedByEvent	[Reaction:R-MMU-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5654335
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-5654684] CBL ubiquitinates FRS2 and FGFR4
(physicalEntity)	[CatalystActivity:10058275] ubiquitin protein ligase activity of Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
(hasComponent)	[Complex:R-MMU-5654363] Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane]
(output)	[Reaction:R-MMU-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4
(inferredTo)	[Complex:R-HSA-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]

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