Reactome | p-Y371-CBL:GRB2 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Mus musculus [Complex:R-MMU-8869163] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] - Mus musculus [Complex:R-MMU-8869163] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4 - Mus musculus [Reaction:R-MMU-5654730] p-CBL:GRB2 binds p-FRS2:activated FGFR3 - Mus musculus [Reaction:R-MMU-5654729] p-CBL:GRB2 binds p-FRS2:activated FGFR2 - Mus musculus [Reaction:R-MMU-5654673] p-CBL:GRB2 binds p-FRS2:activated FGFR1 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10000013
displayName	p-Y371-CBL:GRB2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-MMU-74686] Grb2 [cytosol] [EntityWithAccessionedSequence:R-MMU-182940] phospho-p-Y371-CBL [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-182964] p-Y371-CBL:GRB2 [cytosol] - Homo sapiens
maxDepth	2
name	p-Y371-CBL:GRB2
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-182964
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-MMU-8869163] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] [Complex:R-MMU-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] [Complex:R-MMU-5654267] Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] [Complex:R-MMU-5654307] Activated FGFR3:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] [Complex:R-MMU-5654286] Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] [Complex:R-MMU-182945] EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [plasma membrane]
(input)	[Reaction:R-MMU-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4 [Reaction:R-MMU-5654673] p-CBL:GRB2 binds p-FRS2:activated FGFR1 [Reaction:R-MMU-5654730] p-CBL:GRB2 binds p-FRS2:activated FGFR3 [Reaction:R-MMU-5654729] p-CBL:GRB2 binds p-FRS2:activated FGFR2
(inferredTo)	[Complex:R-HSA-182964] p-Y371-CBL:GRB2 [cytosol]

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