Reactome | Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]

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Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654682] ubiquitin protein ligase activity of Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5654363] Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5654684] CBL ubiquitinates FRS2 and FGFR4 - Homo sapiens
created	[InstanceEdit:5654334] Rothfels, Karen, 2014-12-03
dbId	5654335
displayName	Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
hasComponent	[Complex:R-HSA-5654330] Activated FGFR4:p-FRS2:p-PTPN11 [plasma membrane] [Complex:R-HSA-182964] p-Y371-CBL:GRB2 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Mus musculus [Complex:R-RNO-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Canis familiaris [Complex:R-BTA-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Bos taurus [Complex:R-SSC-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Sus scrofa [Complex:R-DRE-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Danio rerio [Complex:R-XTR-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Gallus gallus [Complex:R-DME-5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - Drosophila melanogaster
isChimeric	false
maxDepth	7
name	Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2
producedByEvent	[Reaction:R-HSA-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5654335
updateTrackers	[UpdateTracker:9893791] Update Tracker - [Complex:5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9893791] Update Tracker - [Complex:5654335] Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane] - v56:[updateContainedComponent]
(hasComponent)	[Complex:R-HSA-5654363] Ub-Activated FGFR4 complex:Ub-p-FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5654684] CBL ubiquitinates FRS2 and FGFR4
(physicalEntity)	[CatalystActivity:5654682] ubiquitin protein ligase activity of Activated FGFR4:p-FRS2:p-PPTN11:p-CBL:GRB2 [plasma membrane]
(output)	[Reaction:R-HSA-5654734] p-CBL:GRB2 binds p-FRS2:activated FGFR4

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