Reactome | Fadd [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Mus musculus [Complex:R-MMU-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] - Mus musculus [Complex:R-MMU-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Mus musculus [Complex:R-MMU-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - Mus musculus [Complex:R-MMU-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Mus musculus [Complex:R-MMU-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-75187] TRAIL:TRAIL receptor trimers bind FADD - Mus musculus [Reaction:R-MMU-75187] TRAIL:TRAIL receptor trimers bind FADD - Mus musculus [Reaction:R-MMU-83650] FasL:Fas binds FADD - Mus musculus [Reaction:R-MMU-83650] FasL:Fas binds FADD - Mus musculus [Reaction:R-MMU-140978] TRADD:TRAF2:RIP1 binds FADD - Mus musculus [Reaction:R-MMU-140978] TRADD:TRAF2:RIP1 binds FADD - Mus musculus [Reaction:R-MMU-2562541] TLR4-induced ripoptosome assembly - Mus musculus [Reaction:R-MMU-2562541] TLR4-induced ripoptosome assembly - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9988617
displayName	Fadd [cytosol]
endCoordinate	208
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol] - Homo sapiens
maxDepth	1
name	Fadd FADD Q61160
referenceEntity	[ReferenceGeneProduct:uniprot:Q61160] UniProt:Q61160
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-54639
startCoordinate	1

(hasComponent)	[Complex:R-MMU-5357809] TRAF2:TRADD:RIPK1(325-671):FADD [cytosol] [Complex:R-MMU-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane] [Complex:R-MMU-43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] [Complex:R-MMU-140977] TRADD:TRAF2:RIPK1:FADD [cytosol] [Complex:R-MMU-2562577] activated TLR4:TRIF:RIP1:FADD [endosome membrane] [Complex:R-MMU-2562542] activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]
(input)	[Reaction:R-MMU-83650] FasL:Fas binds FADD [Reaction:R-MMU-75187] TRAIL:TRAIL receptor trimers bind FADD [Reaction:R-MMU-140978] TRADD:TRAF2:RIP1 binds FADD [Reaction:R-MMU-2562541] TLR4-induced ripoptosome assembly
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-54639] FADD [cytosol]

Fadd [cytosol] Show undefined attributes

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