Reactome | Leptin [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-MMU-2586540] Lep:p-Lepr:p-Jak2 [plasma membrane] - Mus musculus [Complex:R-MMU-2586540] Lep:p-Lepr:p-Jak2 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-2586558] Leptin Binds Leptin Receptor - Mus musculus [Reaction:R-MMU-2586558] Leptin Binds Leptin Receptor - Mus musculus
created	[InstanceEdit:2586546] May, B, 2012-11-15
dbId	2586529
displayName	Leptin [extracellular region]
endCoordinate	167
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-400490] LEP [extracellular region] - Homo sapiens
maxDepth	1
name	Leptin Lep LEP_MOUSE Lep
negativelyRegulates	[NegativeRegulation:10015202] Negative regulation by 'LEP [extracellular region]'
positivelyRegulates	[PositiveRegulation:10012507] Positive regulation by 'LEP [extracellular region]'
referenceEntity	[ReferenceGeneProduct:uniprot:P41160] UniProt:P41160 Lep
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-2586529
startCoordinate	22

(hasComponent)	[Complex:R-MMU-2586540] Lep:p-Lepr:p-Jak2 [plasma membrane] [Complex:R-MMU-2586535] Lep:Lepr:p-Jak2 [plasma membrane] [Complex:R-MMU-2586532] Lep:Lepr:Jak2 [plasma membrane]
(input)	[Reaction:R-MMU-2586558] Leptin Binds Leptin Receptor
(regulator)	[PositiveRegulation:10012507] Positive regulation by 'LEP [extracellular region]' [NegativeRegulation:10015202] Negative regulation by 'LEP [extracellular region]'
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-400490] LEP [extracellular region]

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