Reactome | Lep:Lepr:p-Jak2 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:2586556] protein tyrosine kinase activity of Lep:Lepr:p-Jak2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-2586557] Jak2 Phosphorylates Lepr - Mus musculus
created	[InstanceEdit:2586546] May, B, 2012-11-15
dbId	2586535
displayName	Lep:Lepr:p-Jak2 [plasma membrane]
hasComponent	[Complex:R-MMU-2586525] Lepr:p-Jak2 [plasma membrane] 2 × [EntityWithAccessionedSequence:R-MMU-2586529] Leptin [extracellular region]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	false
literatureReference	[LiteratureReference:873836] Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity
maxDepth	4
modified	[InstanceEdit:2672318] May, B, 2012-11-27
name	Lep:Lepr:p-Jak2
producedByEvent	[Reaction:R-MMU-2586548] Jak2 Autophosphorylates in Response to Leptin - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-2586535

(input)	[Reaction:R-MMU-2586557] Jak2 Phosphorylates Lepr
(physicalEntity)	[CatalystActivity:2586556] protein tyrosine kinase activity of Lep:Lepr:p-Jak2 [plasma membrane]
(output)	[Reaction:R-MMU-2586548] Jak2 Autophosphorylates in Response to Leptin

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