Reactome | Arachidonate metabolism

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Arachidonate metabolism Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10098801
displayName	Arachidonate metabolism
eventOf	[Pathway:R-MMU-8978868] Fatty acid metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9956] arachidonate metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-111883] PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine - Mus musculus [Reaction:R-MMU-5696424] AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters - Mus musculus [Reaction:R-MMU-5693742] FAAH hydrolyses AEA to AA and ETA - Mus musculus [Pathway:R-MMU-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - Mus musculus [Pathway:R-MMU-2142691] Synthesis of Leukotrienes (LT) and Eoxins (EX) - Mus musculus [Pathway:R-MMU-2142688] Synthesis of 5-eicosatetraenoic acids - Mus musculus [Pathway:R-MMU-2142770] Synthesis of 15-eicosatetraenoic acid derivatives - Mus musculus [Pathway:R-MMU-2142712] Synthesis of 12-eicosatetraenoic acid derivatives - Mus musculus [Pathway:R-MMU-2142696] Synthesis of Hepoxilins (HX) and Trioxilins (TrX) - Mus musculus [Pathway:R-MMU-2142816] Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) - Mus musculus [Pathway:R-MMU-2142670] Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) - Mus musculus
inferredFrom	[Pathway:R-HSA-2142753] Arachidonate metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Arachidonate metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2142753
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8978868] Fatty acid metabolism
(inferredTo)	[Pathway:R-HSA-2142753] Arachidonate metabolism

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