Reactome | Synthesis of 5-eicosatetraenoic acids

Schema > Pathway > Entries

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099929
displayName	Synthesis of 5-eicosatetraenoic acids
eventOf	[Pathway:R-MMU-2142753] Arachidonate metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9980] lipoxygenase pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-265296] Arachidonate is oxidised to 5S-HpETE by ALOX5 - Mus musculus [Reaction:R-MMU-8932633] PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE - Mus musculus
inferredFrom	[Pathway:R-HSA-2142688] Synthesis of 5-eicosatetraenoic acids - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of 5-eicosatetraenoic acids
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2142688
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-2142753] Arachidonate metabolism
(inferredTo)	[Pathway:R-HSA-2142688] Synthesis of 5-eicosatetraenoic acids

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